SERVICES & CLIENTS
Here are examples of our current clients and the specific services that we are providing for them.
Genomic Basis of Antibiotic Resistance
We are partnering with the Clinical Microbiology Laboratory of the Emory University Hospital to identify the genomic determinants of antibiotic resistance in Staphylococcus aureus. This work invloves the use of machine learning techniques to model and classiy complete genome sequences of S. aureus strains with different antibiotic resistance profiles.
Genome Regulation, Chromatin & Stem Cell Senescence
We are partnering with the scientists from the Buck Institute for Research on Aging to characterize the changes in chromatin structure and gene regulation that trigger the aging of human adult stem cells. This work involves integrated analyses of transcriptome (RNA-seq), proteome (mass spec) and chromatin (ChIP-seq & MNase-seq) data.
Genomics for Molecular Epidemiliogy
We are partnering with the Meningitis Laboratory of the Centers for Disease Control and Prevention to develop and apply advanced genomic methods for the molecular epidemiological surveillance of bacterial pathogens that cause spinal meningitis. This work involves the analysis of genome sequences to identify novel markers for strain discrimination along with potential genomic determinants of virulence.
Mass Spectrometry & Proteomics for Differential Expression
We are partnering with the scientists from the ThermoFisher BRIMS (Biomarker Research Initiatives in Mass Spectrometry) Center to develop a computational pipeline for the analysis and visualzation of protein differential expression. This work involves the development and application of novel statistical methods for the analysis of tandem mass spectometry profiles.
Development of Bioinformatics Capacity in Latin America
We are partnering with BIOS - the Colombian National Center for Bioinformatics and Computational Biology - to enhance local capacity in bioinformatics and genomics across Latin America. This work involves research collaborations with a number of different institutions in Latin American along with substantial efforts in training, education and outreach. ¡Si se habla español!.